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Railway planning is a complex activity which is usually decomposed into several stages, traditionally network design, line design, timetabling, rolling stock, and staffing. In this paper, we study the design and optimization of train timetables for a rail rapid transit (RRT) line adapted to a dynamic demand environment, which focuses on creating convenient timetables for passengers. The objective is to minimize the average passenger waiting time at the stations, thus focusing on passenger welfare. We first propose two mathematical programming formulations which generalize the non-periodic train timetabling problem on a single line under a dynamic demand pattern. We then analyze the properties of the problem before introducing a fast adaptive large neighborhood search (ALNS) metaheuristic in order to solve large instances of the problem within short computation times. The algorithm yields timetables that may …