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The most significant results obtained during 15 years of research (2004–2019), monitoring, and management in the coral reefs of the Guanahacabibes National Park are presented. The most studied zoological groups have been the hard coral and fish communities. Invasive lionfish (Pterois volitans) have been investigated more specifically, due to the negative impact they cause on invertebrates and native fishes. The studies have been carried out using methodologies developed and validated by national and international experts. Monitoring of the Guanahacabibes National Park, Cuba, suggests that management efforts have had provided important protection to coral reefs and fish communities from 2004 to 2019. Management interventions include the banning of fishing and Acropora cervicornis restoration projects. Effects of these interventions include the following: Coral cover was and fish communities …