Authors
Emil Y Sidky, John Paul Phillips, Weimin Zhou, Greg Ongie, Juan P Cruz‐Bastida, Ingrid S Reiser, Mark A Anastasio, Xiaochuan Pan
Publication date
2021/10
Journal
Medical physics
Volume
48
Issue
10
Pages
6312-6323
Description
Many useful image quality metrics for evaluating linear image reconstruction techniques do not apply to or are difficult to interpret for nonlinear image reconstruction. The vast majority of metrics employed for evaluating nonlinear image reconstruction are based on some form of global image fidelity, such as image root mean square error (RMSE). Use of such metrics can lead to overregularization in the sense that they can favor removal of subtle details in the image. To address this shortcoming, we develop an image quality metric based on signal detection that serves as a surrogate to the qualitative loss of fine image details. The metric is demonstrated in the context of a breast CT simulation, where different equal‐dose configurations are considered. The configurations differ in the number of projections acquired. Image reconstruction is performed with a nonlinear algorithm based on total variation constrained least …
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