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Most reservoir operation practices consider downstream environmental flow as a constraint to meet a minimum release. The resulting flow regime may not necessarily provide downstream aquatic conditions to support healthy ecosystems. These effects can be quantified in terms of changes in values of parameters that represent the flow regimes. Numerous studies have focused on determining the ecological response to hydrological alteration caused by reservoir operation. To mitigate hydrological alteration and restore the natural flow regime as much as possible, a reservoir operation framework is proposed to explicitly incorporate ecological flow requirements. A general optimization-based decision model is presented to consider simultaneously the multiple anthropogenic uses of the reservoir and desirable ecological releases represented by parameters that capture the flow regime. Multiple uses of the reservoir …