Authors
Nicholas Lintzeris, Anjali Bhardwaj, Llewellyn Mills, Adrian Dunlop, Jan Copeland, Iain McGregor, Raimondo Bruno, Jessica Gugusheff, Nghi Phung, Mark Montebello, Therese Chan, Adrienne Kirby, Michelle Hall, Meryem Jefferies, Jennifer Luksza, Marian Shanahan, Richard Kevin, David Allsop
Publication date
2019/9/1
Journal
JAMA internal medicine
Volume
179
Issue
9
Pages
1242-1253
Publisher
American Medical Association
Description
Importance
There are no effective medications for treating dependence on cannabis.
Objective
To examine the safety and efficacy of nabiximols in the treatment of patients with cannabis dependence.
Design, Setting, and Participants
This parallel double-blind randomized clinical trial comparing nabiximols with placebo in a 12-week, multisite outpatient study recruited participants from February 3, 2016, to June 14, 2017, at 4 outpatient specialist alcohol and drug treatment services in New South Wales, Australia. Participants had cannabis dependence (as defined by theInternational Statistical Classification of Diseases and Related Health Problems, Tenth Revision) and were seeking treatment, were nonresponsive to prior treatment attempts, were 18 to 64 years of age, had no other substance use disorder, had no severe medical or psychiatric conditions, were not pregnant, were not mandated by a court to undergo …
Scholar articles
N Lintzeris, A Bhardwaj, L Mills, A Dunlop, J Copeland… - JAMA internal medicine, 2019