Authors
Reed AC Siemieniuk, Maureen O Meade, Pablo Alonso-Coello, Matthias Briel, Nathan Evaniew, Manya Prasad, Paul E Alexander, Yutong Fei, Per O Vandvik, Mark Loeb, Gordon H Guyatt
Publication date
2015/10/6
Source
Annals of internal medicine
Volume
163
Issue
7
Pages
519-528
Publisher
American College of Physicians
Description
Background
Community-acquired pneumonia (CAP) is common and often severe.
Purpose
To examine the effect of adjunctive corticosteroid therapy on mortality, morbidity, and duration of hospitalization in patients with CAP.
Data Sources
MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials through 24 May 2015.
Study Selection
Randomized trials of systemic corticosteroids in hospitalized adults with CAP.
Data Extraction
Two reviewers independently extracted study data and assessed risk of bias. Quality of evidence was assessed with the Grading of Recommendations Assessment, Development, and Evaluation system by consensus among the authors.
Data Synthesis
The median age was typically in the 60s, and …
Scholar articles
RAC Siemieniuk, MO Meade, P Alonso-Coello, M Briel… - Annals of internal medicine, 2015