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Mycobacterium tuberculosis (MTB) is a slow growing pathogen spread through inhalation of air droplets from cough or sneeze of an infected person. MTB typically causes a chronic infection that can be reactivated at anytime. Tuberculosis is highly prevalent in areas with poor nutrition and unsanitary living conditions. Mycobacterium bovis Bacillus Calmette‐Guérin (BCG) is an attenuated strain of Mycobacterium bovis that is widely used as a vaccine against tuberculosis in many parts of the world. However, currently used vaccines differ in characteristics and immunogenicity due to differences in the process of culturing bacterial strains. Furthermore, the efficacy of BCG as a vaccine in adults and adolescents is significantly less than in children as well as more effective against tuberculosis meningitis and miliary tuberculosis than against pulmonary tuberculosis. This low efficacy is hypothesized to be a result of BCG …