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Due to market pressures and increased competition, companies were led to adopt collaborative working practices by creating communication networks and integrated material and product flows. Supply Chain Management is one key to success in this sector, being one recent and powerful operations strategy tool that led to success in many enterprises all over the world. However, it is not affordable to conduct SCM's newest methodologies like Lean, Agile, Resilient and Green being subject to problems of interoperability. This paper presents a model to evaluate the overall business interoperability and establish what measures can reduce interoperability problems in the SC.