Authors
Thomas G Brott, George Howard, Gary S Roubin, James F Meschia, Ariane Mackey, William Brooks, Wesley S Moore, Michael D Hill, Vito A Mantese, Wayne M Clark, Carlos H Timaran, Donald Heck, Pierre P Leimgruber, Alice J Sheffet, Virginia J Howard, Seemant Chaturvedi, Brajesh K Lal, Jenifer H Voeks, Robert W Hobson
Publication date
2016/3/17
Journal
New England Journal of Medicine
Volume
374
Issue
11
Pages
1021-1031
Publisher
Massachusetts Medical Society
Description
Background
In the Carotid Revascularization Endarterectomy versus Stenting Trial, we found no significant difference between the stenting group and the endarterectomy group with respect to the primary composite end point of stroke, myocardial infarction, or death during the periprocedural period or any subsequent ipsilateral stroke during 4 years of follow-up. We now extend the results to 10 years.
Methods
Among patients with carotid-artery stenosis who had been randomly assigned to stenting or endarterectomy, we evaluated outcomes every 6 months for up to 10 years at 117 centers. In addition to assessing the primary composite end point, we assessed the primary end point for the long-term extension study, which was ipsilateral stroke after the periprocedural period.
Results
Among 2502 patients, there was no significant difference in the rate of the primary composite end point between the stenting group …
Scholar articles
TG Brott, G Howard, GS Roubin, JF Meschia, A Mackey… - New England Journal of Medicine, 2016