Authors
Murray B Stein, Alan N Simmons, Justin S Feinstein, Martin P Paulus
Publication date
2007/2
Journal
American Journal of Psychiatry
Volume
164
Issue
2
Pages
318-327
Publisher
American Psychiatric Association
Description
Objective
Increased amygdala reactivity during processing of certain types of emotional stimuli (e.g., fear, anger) has been observed in patients with anxiety disorders such as social phobia and posttraumatic stress disorder (PTSD). It is uncertain whether this heightened amygdala reactivity is specific to treatment-seeking patients with anxiety disorders or is a general feature of individuals with increased anxiety-related temperamental traits.
Method
Thirty-two physically healthy subjects 18–21 years old were recruited from a large pool of college students. Of these, 16 were chosen on the basis of scoring in the upper-15th percentile on a measure of trait anxiety (anxiety-prone group), and 16 were chosen on the basis of scoring in the normative range (40th–60th percentile). Subjects participated in functional magnetic resonance imaging (fMRI) during an emotion face assessment task that has …
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