Authors
Peter A Underhill, Giuseppe Passarino, Alice A Lin, Peidong Shen, M Mirazon Lahr, Robert A Foley, Peter J Oefner, Luigi L Cavalli-Sforza
Publication date
2001/1
Journal
Annals of human genetics
Volume
65
Issue
1
Pages
43-62
Publisher
Cambridge University Press
Description
Although molecular genetic evidence continues to accumulate that is consistent with a recent common African ancestry of modern humans, its ability to illuminate regional histories remains incomplete. A set of unique event polymorphisms associated with the non-recombining portion of the Y-chromosome (NRY) addresses this issue by providing evidence concerning successful migrations originating from Africa, which can be interpreted as subsequent colonizations, differentiations and migrations overlaid upon previous population ranges. A total of 205 markers identified by denaturing high performance liquid chromatography (DHPLC), together with 13 taken from the literature, were used to construct a parsimonious genealogy. Ancestral allelic states were deduced from orthologous great ape sequences. A total of 131 unique haplotypes were defined which trace the microevolutionary trajectory of global modern …
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