Authors
Darren P Martin, Ben Murrell, Arjun Khoosal, Brejnev Muhire
Publication date
2017
Journal
Bioinformatics: Volume I: data, sequence analysis, and evolution
Pages
433-460
Publisher
Springer New York
Description
Recombination between nucleotide sequences is a major process influencing the evolution of most species on Earth. The evolutionary value of recombination has been widely debated and so too has its influence on evolutionary analysis methods that assume nucleotide sequences replicate without recombining. When nucleic acids recombine, the evolution of the daughter or recombinant molecule cannot be accurately described by a single phylogeny. This simple fact can seriously undermine the accuracy of any phylogenetics-based analytical approach which assumes that the evolutionary history of a set of recombining sequences can be adequately described by a single phylogenetic tree. There are presently a large number of available methods and associated computer programs for analyzing and characterizing recombination in various classes of nucleotide sequence datasets. Here we examine the …
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Scholar articles
DP Martin, B Murrell, A Khoosal, B Muhire - Bioinformatics: Volume I: data, sequence analysis, and …, 2017