Authors
Martine Moossdorff, Lori M Van Roozendaal, Luc JA Strobbe, Stefan Aebi, David A Cameron, J Michael Dixon, Armando E Giuliano, Bruce G Haffty, Brigid E Hickey, Clifford A Hudis, V Suzanne Klimberg, Bogda Koczwara, Thorsten Kühn, Marc E Lippman, Anthony Lucci, Martine Piccart, Benjamin D Smith, Vivianne CG Tjan-Heijnen, Cornelis JH Van De Velde, Kimberly J Van Zee, Jan B Vermorken, Giuseppe Viale, Adri C Voogd, Irene L Wapnir, Julia R White, Marjolein L Smidt
Publication date
2014/12/1
Journal
Journal of the National Cancer Institute
Volume
106
Issue
12
Pages
dju288
Publisher
Oxford University Press
Description
Background
In breast cancer studies, many different endpoints are used. Definitions are often not provided or vary between studies. For instance, “local recurrence” may include different components in similar studies. This limits transparency and comparability of results. This project aimed to reach consensus on the definitions of local event, second primary breast cancer, regional and distant event for breast cancer studies.
Methods
The RAND-UCLA Appropriateness method (modified Delphi method) was used. A Consensus Group of international breast cancer experts was formed, including representatives of all involved clinical disciplines. Consensus was reached in two rounds of online questionnaires and one meeting.
Results
Twenty-four international breast cancer experts participated. Consensus was reached on 134 items in four categories. Local …
Scholar articles
M Moossdorff, LM Van Roozendaal, LJA Strobbe… - Journal of the National Cancer Institute, 2014