Autores
Edzard Ernst, Dale E Hammerschmidt, Ulf Bagge, Arpad Matrai, John A Dormandy
Fecha de publicación
1987/5/1
Origen
Jama
Volumen
257
Número
17
Páginas
2318-2324
Editor
American Medical Association
Descripción
Predictive indexes for atherosclerotic risk are imperfect, suggesting that there are predictive factors not commonly considered. Such a factor may be the white blood cell (WBC) count. Epidemiologic studies have shown correlations between the WBC count and the risk of myocardial infarction and stroke. The risk of acute myocardial infarction is approximately four times as great in persons with WBC counts high in the normal range (>9000/μL [9 × 109/L]) as in persons with WBC counts low in the normal range (<6000/μL [6 × 109/L]); only 50% to 65% of the excess risk of the high-count individuals is explainable by tobacco smoking (which covaries with WBC count). A high WBC count also predicts greater risk of reinfarction and of in-hospital death. Less rigorously studied, the constitutional neutropenia of Yemenite Jews appears to afford protection against atherosclerotic disease. Among WBC types, the strongest …
Citas totales
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Artículos de Google Académico
E Ernst, DE Hammerschmidt, U Bagge, A Matrai… - Jama, 1987