Authors
Homie Razavi, Sarah Robbins, Stefan Zeuzem, Francesco Negro, Maria Buti, Ann-Sofi Duberg, Françoise Roudot-Thoraval, Antonio Craxi, Michael Manns, Rui T Marinho, Bela Hunyady, Massimo Colombo, Soo Aleman, Krasimir Antonov, Perttu Arkkila, Kostas Athanasakis, Sarah Blach, Martin Blachier, Antonio J Blasco, Filipe Calinas, Jose L Calleja, Peer B Christensen, Matthew E Cramp, Esther Croes, Robert J de Knegt, Victor de Ledinghen, Jean-Michel Delile, Chris Estes, Karolin Falconer, Martti Färkkilä, Robert Flisiak, Sona Frankova, Ivane Gamkrelidze, Javier García-Samaniego, Jordan Genov, Jan Gerstoft, Liana Gheorghe, Adrian Goldis, Ilias Gountas, Sergeja Gregorčič, Michael Gschwantler, Jessie Gunter, Waldemar Halota, Laura Harcouet, Christophe Hézode, Patrick Hoffmann, Gabor Horvath, Irena Hrstic, Peter Jarčuška, Deian Jelev, Agita Jeruma, Martin Kåberg, Jennifer Kieran, Loreta A Kondili, Iskren Kotzev, Henrik Krarup, Pavol Kristian, Martin Lagging, Wim Laleman, Pablo Lázaro, Valentina Liakina, Boris Lukšić, Matti Maimets, Mihály Makara, Lyudmila Mateva, Mojca Maticic, Francesco S Mennini, Rumiana Mitova, Christophe Moreno, Joel Mossong, Kimberly Murphy, Helen Nde, Vratislav Nemecek, Dijana Nonkovic, Suzanne Norris, Marian Oltman, Anne LH Øvrehus, George Papatheodoridis, Ken Pasini, Devin Razavi-Shearer, Kathryn Razavi-Shearer, Henk W Reesink, Tatjana Reic, Baiba Rozentale, Stephen D Ryder, Riina Salupere, Rui Sarmento-Castro, Christoph Sarrazin, Jonathan D Schmelzer, Ivan Schréter, Carole Seguin-Devaux, Kaarlo Simojoki, Marietta Simonova, Peter J Smit, Kyriakos Souliotis, Danute Speiciene, Jan Sperl, Peter Stärkel, Daniel Struck, Vana Sypsa, Lelia Thornton, Ieva Tolmane, Krzysztof Tomasiewicz, Jonas Valantinas, Pierre Van Damme, David van de Vijver, Adriaan J van der Meer, Daniela van Santen, Hans Van Vlierberghe, Dominique Vandijck, Stefano Vella, Jerneja Videčnik-Zorman, Wolfgang Vogel, Nina Weis, Angelos Hatzakis
Publication date
2017/5/1
Journal
The lancet Gastroenterology & hepatology
Volume
2
Issue
5
Pages
325-336
Publisher
Elsevier
Description
Background
Hepatitis C virus (HCV) is a leading cause of liver-related morbidity and mortality worldwide. In the European Union (EU), treatment and cure of HCV with direct-acting antiviral therapies began in 2014. WHO targets are to achieve a 65% reduction in liver-related deaths, a 90% reduction of new viral hepatitis infections, and 90% of patients with viral hepatitis infections being diagnosed by 2030. This study assessed the prevalence of HCV in the EU and the level of intervention required to achieve WHO targets for HCV elimination.
Methods
We populated country Markov models for the 28 EU countries through a literature search of PubMed and Embase between Jan 1, 2000, and March 31, 2016, and a Delphi process to gain expert consensus and validate inputs. We aggregated country models to create a regional EU model. We used the EU model to forecast HCV disease progression (considering the effect …
Scholar articles
H Razavi, S Robbins, S Zeuzem, F Negro, M Buti… - The lancet Gastroenterology & hepatology, 2017
H Razavi, S Robbins, S Zeuzem, F Negro, M Buti… - The lancet Gastroenterology & hepatology, 2017