Authors
Jihyun An, Steven J Geib, Nathaniel L Rosi
Publication date
2009/6/24
Journal
Journal of the American Chemical Society
Volume
131
Issue
24
Pages
8376-8377
Publisher
American Chemical Society
Description
A porous anionic metal-organic framework, bio-MOF-1, constructed using adenine as a biomolecular building block is described. The porosity of this material is evaluated, its stability in biological buffers is studied, and its potential as a material for controlled drug release is investigated. Specifically, procainamide HCl is loaded into the pores of bio-MOF-1 using a simple cation exchange process. Exogenous cations from biological buffers are shown to affect the release of the adsorbed drug molecules.
Total citations
Scholar articles
J An, SJ Geib, NL Rosi - Journal of the American Chemical Society, 2009