Authors
Kwong T Quach, Linda Dirven, Aliede M Vingerhoed, Jeroen de Bresser, Ruben Dammers, Eelke M Bos, Wouter A Moojen, Wilco C Peul, Martin JB Taphoorn, Amir H Zamanipoor Najafabadi, Wouter R van Furth
Publication date
2023/1/1
Journal
Neuro-Oncology Advances
Volume
5
Issue
1
Pages
vdad056
Publisher
Oxford University Press
Description
Background
Fatigue is a commonly reported and severe symptom in primary brain tumor patients, but the exact occurrence in meningioma patients is unknown. This study aimed to determine the frequency and severity of fatigue in meningioma patients as well as associations between the level of fatigue and patient-, tumor-, and treatment-related factors.
Methods
In this multicenter cross-sectional study, meningioma patients completed questionnaires on fatigue (MFI-20), sleep (PSQI), anxiety and depression (HADS), tumor-related symptoms (MDASI-BT), and cognitive functioning (MOS-CFS). Multivariable regression models were used to evaluate the independent association between fatigue and each patient-, tumor-, and treatment-related factor separately, corrected for relevant confounders.
Results
Based on predetermined in- and exclusion criteria, 275 …