Authors
Daniel Ang, Robert Sykes, Anna Kamdar, Conor Bradley, Jaclyn Carberry, David Carrick, Peter McCartney, Angie Ghattas, Richard Brogan, Keith Robertson, Francis Joshi, Aadil Shaukat, Stuart Hood, Stuart Watkins, Paul Rocchiccioli, Hany Eteiba, Mitchell Lindsay, Richard Good, Ross McGeoch, Damien Collison, Alex McConnachie, Colin Berry
Publication date
2024/6/1
Source
Heart
Volume
110
Issue
Suppl 3
Pages
A218-A218
Publisher
BMJ Publishing Group Ltd and British Cardiovascular Society
Description
Background and Aims
Coronary function testing to measure index of microcirculatory resistance (IMR) and coronary flow reserve (CFR) may be performed at the time of invasive coronary angiography to aid the diagnosis of microvascular angina. Intravenous (IV) adenosine infusion is used to induce stable hyperaemia. Logistics and systemic side-effects limit clinical adoption. Iodinated contrast medium (iohexol) is used during standard diagnostic angiography and induces transient, submaximal hyperaemia. We investigated the feasibility and diagnostic value of contrast-derived indices of coronary microvascular function.
Methods and Results
Consecutive patients with suspected angina who underwent clinically-indicated invasive coronary angiography at 2 regional cardiac centres between Jul 2021 and Nov 2022 were included. Coronary function testing was performed using a temperature/pressure diagnostic …
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