Authors
Jamie Layland, Keith G Oldroyd, Nick Curzen, Arvind Sood, Kanarath Balachandran, Raj Das, Shahid Junejo, Nadeem Ahmed, Matthew MY Lee, Aadil Shaukat, Anna O'Donnell, Julian Nam, Andrew Briggs, Robert Henderson, Alex McConnachie, Colin Berry, Andrew Hannah, Andrew Stewart, Malcolm Metcalfe, John Norrie, Saqib Chowdhary, Andrew Clark, Robert Henderson, Kanarath Balachandran, Colin Berry, Gordon Baird, Anna O'Donnell, Arvind Sood, Nick Curzen, Raj Das, Ian Ford, Jamie Layland, Shahid Junejo, Keith Oldroyd
Publication date
2015/1/7
Journal
European heart journal
Volume
36
Issue
2
Pages
100-111
Publisher
The University of Chicago Press
Description
Aim
We assessed the management and outcomes of non-ST segment elevation myocardial infarction (NSTEMI) patients randomly assigned to fractional flow reserve (FFR)-guided management or angiography-guided standard care.
Methods and results
We conducted a prospective, multicentre, parallel group, 1 : 1 randomized, controlled trial in 350 NSTEMI patients with ≥1 coronary stenosis ≥30% of the lumen diameter assessed visually (threshold for FFR measurement) (NCT01764334). Enrolment took place in six UK hospitals from October 2011 to May 2013. Fractional flow reserve was disclosed to the operator in the FFR-guided group (n = 176). Fractional flow reserve was measured but not disclosed in the angiography-guided group (n = 174). Fractional flow reserve ≤0.80 was an indication for revascularization by percutaneous coronary intervention (PCI) or coronary …
Scholar articles
J Layland, KG Oldroyd, N Curzen, A Sood… - European heart journal, 2015
J Layland, KG Oldroyd, N Curzen, A Sood… - European Heart Journal, 2015