Authors
Peter Bower, Evangelos Kontopantelis, Alex Sutton, Tony Kendrick, David A Richards, Simon Gilbody, Sarah Knowles, Pim Cuijpers, Gerhard Andersson, Helen Christensen, Björn Meyer, Marcus Huibers, Filip Smit, Annemieke Van Straten, Lisanne Warmerdam, Michael Barkham, Linda Bilich, Karina Lovell, Emily Tung-Hsueh Liu
Publication date
2013/2/26
Journal
Bmj
Volume
346
Publisher
British Medical Journal Publishing Group
Description
Objective To assess how initial severity of depression affects the benefit derived from low intensity interventions for depression.
Design Meta-analysis of individual patient data from 16 datasets comparing low intensity interventions with usual care.
Setting Primary care and community settings.
Participants 2470 patients with depression.
Interventions Low intensity interventions for depression (such as guided self help by means of written materials and limited professional support, and internet delivered interventions).
Main outcome measures Depression outcomes (measured with the Beck Depression Inventory or Center for Epidemiologic Studies Depression Scale), and the effect of initial depression severity on the effects of low intensity interventions.
Results Although patients were referred for low intensity interventions, many had moderate to severe depression at baseline. We found a significant interaction between …
Total citations
201320142015201620172018201920202021202220232024112732314045294239332618