Authors
Zeyu Chen, Shi Qiu, Chichen Zhang, Yu Zhan, Liangren Liu, Yige Bao, Bo Chen, Yunjin Bai, Xiaonan Zheng, Yin Huang, Kun Jin, Ping Han, Qiang Wei
Publication date
2022/3
Journal
Andrology
Volume
10
Issue
3
Pages
567-575
Description
Background
Exposure to environmental pollution via different mechanisms is associated with multiple endocrine dysfunctions. Organophosphate esters (OPEs) are endocrine‐disrupting chemicals that affect sex steroid hormones.
Purpose
We aimed to study the effect of OPEs and their metabolites, such as diphenyl phosphate (DPHP), bis(1,3‐dichloro‐2‐propyl) phosphate (BDCPP), bis(2‐chloroethyl) phosphate (BCEP), and dibutyl phosphate (DBUP), on sex steroid hormones in males.
Design, setting, participants, and intervention
This cross‐sectional analytical study analyzed data from the 2013–2014 National Health and Nutrition Examination Survey among 763 male participants aged ≥20 years.
Main outcome measures
The relationships between the metabolites of OPEs and total testosterone, estradiol, sex hormone‐binding globulin, and the ratio of total testosterone to estradiol (a parameter derived …
Total citations
Scholar articles
Z Chen, S Qiu, C Zhang, Y Zhan, L Liu, Y Bao, B Chen… - Andrology, 2022