Authors
Wentian Li, Kaitao Lai, Neha Chopra, Zhaomin Zheng, Abhirup Das, Ashish D Diwan
Publication date
2022/4
Source
European Spine Journal
Volume
31
Issue
4
Pages
917-925
Publisher
Springer Berlin Heidelberg
Description
Purpose
Low back pain (LBP), a widely prevalent and costly disease around the world, is mainly caused by intervertebral disc (IVD) degeneration (IDD). Although numerous factors may trigger this degenerative process, microbiome dysbiosis has recently been implicated as one of the likely causes. However, the exact relationship between the microbiome and IDD is not well understood. This review summarizes the potential mechanisms and discusses microbiome dysbiosis’s possible influence on IDD and LBP.
Methods
Total citations
Scholar articles
W Li, K Lai, N Chopra, Z Zheng, A Das, AD Diwan - European Spine Journal, 2022