Authors
Gianluca Farrugia, Christian Saliba, Jelena Pistolic, Vladimir Benes, Neville Vassallo, Godfrey Grech, Joseph J Borg, William H Bannister, Rena Balzan
Publication date
2015
Publisher
University of Malta. Faculty of Medicine and Surgery
Description
Acetylcoenzyme A (acetyl-CoA) plays an important role in cellular metabolism. It is an essential substrate for energy production in the tricarboxylic acid (TCA) cycle. In yeast cells grown on ethanol as the carbon source, acetyl-CoA is generated in the peroxisomes and cytosol, and then transpOlted into mitochondria by the carnitine shuttle pathway. We use yeast as a eukaryotic model since it offers large experimental advantages in conditions controlled by multiple genes.
Scholar articles
G Farrugia, C Saliba, J Pistolic, V Benes, N Vassallo… - 2015