Authors
Dimitrios Karantanis, Brian P O'Neill, Rathan M Subramaniam, Robert J Witte, Brian P Mullan, Mark A Nathan, Val J Lowe, Patrick J Peller, Gregory A Wiseman
Publication date
2007/11/1
Journal
Nuclear medicine communications
Volume
28
Issue
11
Pages
834-841
Publisher
LWW
Description
Objective
To determine the value of 18 F-FDG PET/CT in the different manifestations of primary central nervous system lymphoma (PCNSL) in HIV-negative patients.
Methods
All PCNSL and HIV-negative patients referred for PET/CT in our institution from July 2001 to June 2006 were retrospectively studied. PET/CT examinations were reviewed by two experienced readers and evaluated for each possible anatomical site of nervous system involvement: cerebral, spinal/nerve and ocular. PET/CT results were characterized as true positive or negative and false positive or negative according to the status of the disease, which was determined after the evaluation of biopsies, laboratory, clinical and imaging examinations, and follow-up.
Results
Forty-two PET/CT examinations were carried out in 25 PCNSL patients. For intracerebral disease, PET/CT was true positive in 13 cases, true negative in 27 and false negative in two …
Total citations
Scholar articles
D Karantanis, BP O'Neill, RM Subramaniam, RJ Witte… - Nuclear medicine communications, 2007