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Purpose:

Knowing the glycolytic phenotype of cancers is important for the appropriate use of F-18 FDG PET/CT imaging. This study was performed to determine the influence of tumor grade and histology on the glycolytic phenotype of epithelial ovarian cancer patients.

Materials and Methods:

Only histopathologically confirmed epithelial ovarian cancer patients, with no other concurrent malignancies, who had F-18 FDG PET/CT either before or at least 3 months after any therapeutic intervention and had confirmed measurable disease of> 1 cm were included. The F-18 FDG PET/CT uptake was determined as maximum standard uptake value (SUV max) at the pathologically confirmed site of disease or in the most active lesion. SUV max was correlated to tumor grade and histology.

Results:

Of 171 ovarian cancer patients, 42 referred for F-18 FDG PET/CT scans between January 2003 and December 2010 were eligible …