Authors
David Atkins, Peter A Briss, Martin Eccles, Signe Flottorp, Gordon H Guyatt, Robin T Harbour, Suzanne Hill, Roman Jaeschke, Alessandro Liberati, Nicola Magrini, James Mason, Dianne O'Connell, Andrew D Oxman, Bob Phillips, Holger Schünemann, Tessa Edejer, Gunn E Vist, John W Williams
Publication date
2005/3/23
Journal
BMC Health Services Research
Volume
5
Issue
1
Pages
1
Publisher
BioMed Central
Description
Background
Systems that are used by different organisations to grade the quality of evidence and the strength of recommendations vary. They have different strengths and weaknesses. The GRADE Working Group has developed an approach that addresses key shortcomings in these systems. The aim of this study was to pilot test and further develop the GRADE approach to grading evidence and recommendations.
Methods
A GRADE evidence profile consists of two tables: a quality assessment and a summary of findings. Twelve evidence profiles were used in this pilot study. Each evidence profile was made based on information available in a systematic review. Seventeen people were given instructions and independently graded the level of evidence and strength of recommendation for each of the 12 evidence profiles. For each example judgements …
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