Authors
Sydney M Finegold, Denise Molitoris, Yuli Song, Chengxu Liu, Marja-Liisa Vaisanen, Ellen Bolte, Maureen McTeague, Richard Sandler, Hannah Wexler, Elizabeth M Marlowe, Matthew D Collins, Paul A Lawson, Paula Summanen, Mehmet Baysallar, Thomas J Tomzynski, Erik Read, Eric Johnson, Rial Rolfe, Palwasha Nasir, Haroun Shah, David A Haake, Patricia Manning, Ajay Kaul
Publication date
2002/9/1
Journal
Clinical Infectious Diseases
Volume
35
Issue
Supplement_1
Pages
S6-S16
Publisher
The University of Chicago Press
Description
Some cases of late-onset (regressive) autism may involve abnormal flora because oral vancomycin, which is poorly absorbed, may lead to significant improvement in these children. Fecal flora of children with regressive autism was compared with that of control children, and clostridial counts were higher. The number of clostridial species found in the stools of children with autism was greater than in the stools of control children. Children with autism had 9 species of Clostridium not found in controls, whereas controls yielded only 3 species not found in children with autism. In all, there were 25 different clostridial species found. In gastric and duodenal specimens, the most striking finding was total absence of non—spore-forming anaerobes and microaerophilic bacteria from control children and significant numbers of such bacteria from children with autism. These studies demonstrate significant alterations in the …
Total citations
Scholar articles
SM Finegold, D Molitoris, Y Song, C Liu, ML Vaisanen… - Clinical Infectious Diseases, 2002