Authors
Rolf Apweiler, Henning Hermjakob, Nathan Sharon
Publication date
1999/12/17
Source
Biochimica et Biophysica Acta (BBA)-General Subjects
Volume
1473
Issue
1
Pages
4-8
Publisher
Elsevier
Description
The SWISS-PROT protein sequence data bank contains at present nearly 75 000 entries, almost two thirds of which include the potential N-glycosylation consensus sequence, or sequon, NXS/T (where X can be any amino acid but proline) and thus may be glycoproteins. The number of proteins filed as glycoproteins is however considerably smaller, 7942, of which 749 have been characterized with respect to the total number of their carbohydrate units and sites of attachment of the latter to the protein, as well as the nature of the carbohydrate-peptide linking group. Of these well characterized glycoproteins, about 90% carry either N-linked carbohydrate units alone or both N- and O-linked ones, attached at 1297 N-glycosylation sites (1.9 per glycoprotein molecule) and the rest are O-glycosylated only. Since the total number of sequons in the well characterized glycoproteins is 1968, their rate of occupancy is 2/3 …
Total citations
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Scholar articles
R Apweiler, H Hermjakob, N Sharon - Biochimica et Biophysica Acta (BBA)-General Subjects, 1999