Authors
Nancy M Dunbar, Mark H Yazer, OPTIMUS Study Investigators on behalf of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative, Naama Warman Alaluf, Ramir M Alcantara, Torunn O Apelseth, Milos Bohonek, Martin Ellis, Roberta Fachini, Emmanuel A Fadeyi, Peter Flanagan, Sabine Flommersfeld, Nico Greger, Mara Hareuveni, Sarah K Harm, Tina S Ipe, Mary Rose Jones, Volker Kiefel, Dawn Kosaka‐Nguyen, Jose Mauro Kutner, Ang Ai Leen, Faisal Mukhtar, Michael F Murphy, Mira Naamad, Susan N Nahirniak, Deborah J Novak, Kerry L O'Brien, Monica B Pagano, Victoria Peer, Naomi Rahimi‐Levene, Kathleen Selleng, Lawrence Sham, Yehudit Sharon, Andrew Wei‐Yeh Shih, Maayan Shiner, Julie H Simmons, Romi Sinha, Janus Slonka, Julie Staves, James R Stubbs, Tamar Tadmor, Rick Tocchetti, Lynne Uhl, Silvano Wendel, Ana Paula H Yokoyama, Alyssa Ziman
Publication date
2018/6
Journal
Transfusion
Volume
58
Issue
6
Pages
1348-1355
Description
BACKGROUND
Despite conservation strategies, shortages of O– red blood cells (RBCs) occur. The goal of this study was to determine how utilization of O– RBCs can be reduced using age‐ and location‐based O+ substitution for routine transfusions in O– patients during O– shortages.
STUDY DESIGN AND METHODS
Recipient age and ABO and D group were obtained for allogeneic RBC transfusions during the 2016 calendar year from 31 participating centers. ABO and D group of each RBC unit was compared to that of the recipient to determine the number of O– RBC units transfused to all patients, the number of RBC units transfused to O– patients, and the number of O– RBC units transfused to O– patients. O– RBC transfusions to O– patients were further analyzed by patient age and location.
RESULTS
The fraction of all transfused RBCs that were O– at the participating centers ranged from 3.0% to 13.9 …
Scholar articles
NM Dunbar, MH Yazer… - Transfusion, 2018