Authors
Amit Kaura, Jonathan AC Sterne, Adam Trickey, Abdulrahim Mulla, Benjamin Glampson, Jim Davies, Vasileios Panoulas, Kerrie Woods, Anoop D Shah, Paul Elliott, Harry Hemingway, Bryan Williams, Folkert W Asselbergs, Narbeh Melikian, Divaka Perera, Rajesh Kharbanda, Riyaz S Patel, Ajay M Shah, Keith M Channon, Jamil Mayet
Publication date
2022/6/1
Source
Heart
Volume
108
Issue
Suppl 1
Pages
A27-A28
Publisher
BMJ Publishing Group Ltd and British Cardiovascular Society
Description
Introduction
It has been challenging for researchers to access granular electronic health record (EHR) data at scale. The NIHR Health Informatics Collaborative (HIC) enables the sharing of routine EHR data across NHS hospitals for research. One emerging prospect is to use big data to traverse the translational spectrum. As an early discovery phase study, we estimated the effect of invasive versus non-invasive management on the survival of patients with non-ST elevation myocardial infarction (NSTEMI) aged 80 years or older (SENIOR-NSTEMI Study). As a later implementation phase study, we determined the relationship between the full spectrum of troponin level and mortality in patients in whom troponin testing was performed for clinical purposes (TROP-RISK Study).
Methods
Five NHS Trusts contributed data: Imperial, University College London, Oxford, King’s and Guy’s and St Thomas’. We used Microsoft …
Scholar articles
A Kaura, JAC Sterne, A Trickey, A Mulla, B Glampson… - 2022