Authors
Amit Kaura, Adam Hartley, Vasileios Panoulas, Ben Glampson, Jim Davies, Abdulrahim Mulla, Kerrie Woods, Joe Omigie, Anoop D Shah, Keith Channon, Jonathan N Weber, Mark R Thursz, Paul Elliott, Harry Hemingway, Bryan Williams, Folkert Asselbergs, Michael O’Sullivan, Dorian Haskard, Graham Lord, Narbeh Melikian, Daryl Francis, Wolfgang Koenig, Divaka Perera, Ajay Shah, Rajesh Kharbanda, Riyaz Patel, Jamil Mayet, Ramzi Khamis
Publication date
2019/5/1
Source
Heart
Volume
105
Issue
Suppl 6
Pages
A120-A121
Publisher
BMJ Publishing Group Ltd and British Cardiovascular Society
Description
Background
The incremental long-term prognostic value of high-sensitivity C-reactive protein (hsCRP) above troponin in a large real-world cohort of unselected patients presenting with suspected acute coronary syndromes (ACS) is unknown. We hypothesised that a mildly elevated hsCRP is associated with mortality risk in patients with suspected ACS, independent of troponin level.
Methods
We used the National Institute for Health Research Health Informatics Collaborative data of 257,948 patients who had a troponin measured at 5 cardiac centres. We excluded patients with clinically abnormal white cell counts and hsCRP >15 mg/L to try limiting the population to those without overt infections, malignancies or systemic inflammatory conditions that may confound our analyses. Patients were divided into four hsCRP groups (<2, 2–4.9, 5–9.9 and 10–15 mg/L) and the association between hsCRP levels and all-cause …
Scholar articles
A Kaura, A Hartley, V Panoulas, B Glampson, J Davies… - 2019