Authors
Amit Kaura, Vasileios Panoulas, Ben Glampson, Jim Davies, Abdulrahim Mulla, Kerrie Woods, Joe Omigie, Anoop D Shah, Keith Channon, Jonathan N Weber, Mark R Thursz, Paul Elliott, Harry Hemingway, Bryan Williams, Folkert Asselbergs, Michael O’Sullivan, Graham Lord, Narbeh Melikian, Rajesh Kharbanda, Ajay Shah, Divaka Perera, Riyaz Patel, Daryl Francis, Jamil Mayet
Publication date
2019/5/1
Source
Heart
Volume
105
Issue
Suppl 6
Pages
A121-A121
Publisher
BMJ Publishing Group Ltd and British Cardiovascular Society
Description
Background
In the past two decades, assays for troponin have undergone vast improvements, allowing fast detection of troponin with increased precision. With improved sensitivity of current troponin assays, more patients end up with a positive troponin result. There is limited data to help inform the implications of a positive troponin test across the age spectrum, in clinical practice. The aim of this study was to investigate the overall prognostic impact of a positive troponin result on all-cause mortality in patients in whom troponin testing has been done for clinical purposes.
Methods
The NIHR Health Informatics Collaborative (NHIC) project was established to enable the sharing and repurposing of routinely captured clinical data for re-use in research. All troponin values measured during the study period (generally 2010 to 2017) were assembled from five contributing cardiovascular centres. The results were …
Scholar articles