Authors
Amit Kaura, Sahil Goswami, Umberto Benedetto, Abdulrahim Mulla, Benjamin Glampson, Vasileios Panoulas, Jim Davies, Kerrie Woods, Sanjay Gautama, Anoop D Shah, Paul Elliott, Harry Hemingway, Bryan Williams, Folkert W Asselbergs, Narbeh Melikian, Ajay M Shah, Divaka Perera, Rajesh Kharbanda, Riyaz S Patel, Keith M Channon, Jennifer Quint, Jamil Mayet
Publication date
2022/6/1
Journal
Heart
Volume
108
Issue
Suppl 1
Pages
A129-A129
Publisher
BMJ Publishing Group LTD
Description
Background
A positive cardiac troponin (cTn) is an independent predictor of short-term mortality in individuals presenting with acute pulmonary embolism (PE). However, there is limited evidence regarding the impact age has on the association between cTn levels and mortality in patients with PE. The aim of our study was to investigate the relationship between cTn level, age, and all-cause mortality, in hospitalised patients with a PE.
Methods
A retrospective cohort study using the National Institute for Health Research Health Informatics Collaborative Cardiovascular dataset of all consecutive patients who had a troponin measured at five hospitals (Imperial, University College London, Oxford, King’s and Guy’s and St Thomas’) between 2010 and 2017. Patients admitted to hospital with a primary diagnosis of PE with at least one cTn measurement were included. Survival analyses were performed using multivariate Cox …