Authors
Hélène Vulser, Hervé S Lemaître, Stella Guldner, Pauline Bezivin-Frère, Martin Löffler, Anna S Sarvasmaa, Jessica Massicotte-Marquez, Eric Artiges, Marie-Laure Paillère Martinot, Irina Filippi, Ruben Miranda, Argyris Stringaris, Betteke Maria van Noort, Jani Penttilä, Yvonne Grimmer, Andreas Becker, Tobias Banaschewski, Arun LW Bokde, Sylvane Desrivières, Juliane H Fröhner, Hugh Garavan, Antoine Grigis, Penny A Gowland, Andreas Heinz, Dimitri Papadopoulos Orfanos, Luise Poustka, Michael N Smolka, Philip A Spechler, Henrik Walter, Robert Whelan, Gunter Schumann, Herta Flor, Jean-Luc Martinot, Frauke Nees, IMAGEN Consortium
Publication date
2023/1/1
Journal
Journal of the American Academy of Child & Adolescent Psychiatry
Volume
62
Issue
1
Pages
48-58
Publisher
Elsevier
Description
Objective
Adolescence is a critical period for circadian rhythm, with a strong shift toward eveningness around age 14. Also, eveningness in adolescence has been found to predict later onset of depressive symptoms. However, no previous study has investigated structural variations associated with chronotype in early adolescence and how this adds to the development of depressive symptoms.
Method
Assessment of 128 community-based adolescents (51% girls) at age 14 and 19 years was performed. Using whole-brain voxel-based morphometry, baseline (at age 14) regional gray matter volumes (GMVs), follow-up (at age 19) regional GMVs, and longitudinal changes (between 14 and 19) associated with Morningness/Eveningness Scale in Children score and sleep habits at baseline were measured. The association of GMV with depressive symptoms at 19 years was studied, and the role of potential clinical and …
Total citations
Scholar articles
H Vulser, HS Lemaître, S Guldner, P Bezivin-Frère… - Journal of the American Academy of Child & …, 2023