Authors
Annelies Cannaert
Description
Dr. Christophe Stove is a professor in the Laboratory of Toxicology at Ghent University with roles in education, toxicology testing and research. His laboratory research includes investigating molecular mechanisms that control G-proteincoupled receptor (GPCR) signaling, studying the role of related protein: protein interactions (PPI), and developing novel bioassays to determine the biological activity of diverse compounds in biological matrices. His lab has recently focused on the development of screening assays for synthetic “designer” drugs. Here, Annelies Cannaert, a former graduate student and current post-doctoral fellow in Dr. Stove’s lab, describes her work using NanoBiT® PPI Assay to measure the GPCR/β-arrestin 2 interaction as a marker of GPCR activation to develop novel untargeted screening assays for the detection of synthetic opioids and cannabinoids.