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Objective: Assessment of a possible relationship between perception of satiety and diet-induced thermogenesis, with different macronutrient compositions, in a controlled situation over 24 h.

Design: Two diets with different macronutrient compositions were offered to all subjects in randomized order.

Setting: The study was executed in the respiration chambers at the department of Human Biology, Maastricht University.

Subjects: Subjects were eight females, ages 23–33 y, BMI 23±3 kg/m 2, recruited from University staff and students.

Interventions: Subjects were fed in energy balance, with protein/carbohydrate/fat: 29/61/10 and 9/30/61 percentage of energy, with fixed meal sizes and meal intervals, and a fixed activity protocol, during 36 h experiments in a respiration chamber. The appetite profile was assessed by questionnaires during the day and during meals. Diet induced thermogenesis was determined as part of …