Authors
Shweta Bagewadi, Tamara Bobić, Martin Hofmann-Apitius, Juliane Fluck, Roman Klinger
Publication date
2014
Journal
F1000Research
Volume
3
Publisher
Faculty of 1000 Ltd
Description
Introduction: MicroRNAs (miRNAs) have demonstrated their potential as post-transcriptional gene expression regulators, participating in a wide spectrum of regulatory events such as apoptosis, differentiation, and stress response. Apart from the role of miRNAs in normal physiology, their dysregulation is implicated in a vast array of diseases. Dissection of miRNA-related associations are valuable for contemplating their mechanism in diseases, leading to the discovery of novel miRNAs for disease prognosis, diagnosis, and therapy.
Motivation: Apart from databases and prediction tools, miRNA-related information is largely available as unstructured text. Manual retrieval of these associations can be labor-intensive due to steadily growing number of publications. Additionally, most of the published miRNA entity recognition methods are keyword based, further subjected to manual inspection for retrieval of relations …
Total citations
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Scholar articles
S Bagewadi, T Bobić, M Hofmann-Apitius, J Fluck… - F1000Research, 2014