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Present research work emphasizes the integrated approach of heavy metal pollution indices coupled with multivariate statistical analysis to evaluate the health risk from groundwater of the Kadava River Basin. In view of this, forty representative groundwater samples were collected from dug and bore wells during pre-monsoon seasons of 2011 from rural habitations which are actively used for drinking and irrigation. The heavy metals viz., Pb, Cd, Zn, Fe, Mn, Cr, Cu, Co and Ni were analyzed through ICP-AES and compared with the BIS standards for drinking appropriateness. The analytical results exhibited that, Pb and Ni exceeded the maximum allowable concentration in all samples; while, Cr in 95% samples and Fe in 92.5% samples found beyond the safe limits. Heavy metal contamination assessment has been performed by using Heavy metal Pollution Index (HPI), Hazard Index (HI), Heavy metal …