Authors
Omer Bonne, Asaf Gilboa, Yoram Louzoun, Dalia Brandes, Ilan Yona, Hava Lester, Gavriel Barkai, Nanette Freedman, Roland Chisin, Arieh Y Shalev
Publication date
2003/11/15
Journal
Biological psychiatry
Volume
54
Issue
10
Pages
1077-1086
Publisher
Elsevier
Description
BACKGROUND
Brain imaging research in posttraumatic stress disorder has been largely performed on patients with chronic disease, often heavily medicated, with current or past alcohol and substance abuse. Additionally, virtually only activation brain imaging paradigms have been done in posttraumatic stress disorder, whereas in other mental disorders both resting and activation studies have been performed.
METHODS
Twenty-eight (11 posttraumatic stress disorder) trauma survivors underwent resting state hexamethylpropyleneamineoxime single photon emission computed tomography and magnetic resonance imaging 6 months after trauma. Eleven nontraumatized subjects served as healthy controls.
RESULTS
Regional cerebral blood flow in the cerebellum was higher in posttraumatic stress disorder than in both control groups. Regional cerebral blood flow in right precentral, superior temporal, and fusiform …
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Scholar articles
O Bonne, A Gilboa, Y Louzoun, D Brandes, I Yona… - Biological psychiatry, 2003