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It is difficult to formulate and solve optimization problems for sustainability performance in manufacturing. The main reasons for this are: (1) optimization problems are typically complex and involve manufacturing and sustainability aspects, (2) these problems require diversity of manufacturing data, (3) optimization modeling and solving tasks require specialized expertise and programming skills, (4) the use of a different optimization application requires re-modeling of optimization problems even for the same problem, and (5) these optimization models are not decomposed nor reusable. This paper presents the development of a decision support system (DSS) that enables manufacturers to formulate optimization problems at multiple manufacturing levels, to represent various manufacturing data, to create compatible and reusable models and to derive easily optimal solutions for improving sustainability …