Authors
Sunil A Sheth, Bryan Yoo, Jeffrey L Saver, Sidney Starkman, Latisha K Ali, Doojin Kim, Nestor R Gonzalez, Reza Jahan, Satoshi Tateshima, Gary Duckwiler, Fernando Vinuela, David S Liebeskind
Publication date
2015/7/1
Journal
Journal of neurointerventional surgery
Volume
7
Issue
7
Pages
478-483
Publisher
British Medical Journal Publishing Group
Description
Background
The ideal population of patients for endovascular therapy (ET) in acute ischemic stroke remains undefined. Recent ET trials have moved towards selecting patients with proximal middle cerebral artery (MCA) or internal carotid artery occlusions, which will likely leave a gap in our understanding of the treatment outcomes of M2 occlusions.
Objective and methods
To examine the presentation, treatment, and outcomes of M2 compared with M1 MCA occlusions in patients undergoing ET by assessing comprehensive MRI, angiography, and clinical data.
Results
We found that M2 occlusions can lead to massive strokes defined by hypoperfused and infarcted volumes as well as death or moderate to severe disability in nearly 50% of patients at discharge. Compared with M1 occlusions, M2 occlusions achieved similar Thrombolysis in Cerebral Infarction (TICI) 2b/3 recanalization rates, with significantly less …
Scholar articles
SA Sheth, B Yoo, JL Saver, S Starkman, LK Ali, D Kim… - Journal of neurointerventional surgery, 2015