Authors
MA Urbin, Dylan A Royston, Douglas J Weber, Michael L Boninger, Jennifer L Collinger
Publication date
2019/1/1
Source
Neurobiology of disease
Volume
121
Pages
286-295
Publisher
Academic Press
Description
Motor output maps within primary motor cortex are widely distributed and modified by motor skill learning and neurological injury. Functions that these maps represent after spinal cord injury remain debatable. Moreover, the pattern of reorganization and whether it supports recovery of compromised motor function is not well understood. A deeper understanding of the pathophysiological mechanisms of motor dysfunction after spinal cord injury is necessary to develop and optimize repair strategies. There are three purposes for this review. The first is to synthesize available research on spontaneous reorganization with primary motor cortex following spinal cord injury. The second is to draw on existing evidence from the motor skill learning and brain injury literature to interpret the form and purpose of motor maps. The third purpose is to account for the existing research on intervention-induced reorganization of primary …
Total citations
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