Authors
Gustavo De Los Campos, Hugo Naya, Daniel Gianola, José Crossa, Andrés Legarra, Eduardo Manfredi, Kent Weigel, José Miguel Cotes
Publication date
2009/5/1
Journal
Genetics
Volume
182
Issue
1
Pages
375-385
Publisher
Oxford University Press
Description
The availability of genomewide dense markers brings opportunities and challenges to breeding programs. An important question concerns the ways in which dense markers and pedigrees, together with phenotypic records, should be used to arrive at predictions of genetic values for complex traits. If a large number of markers are included in a regression model, marker-specific shrinkage of regression coefficients may be needed. For this reason, the Bayesian least absolute shrinkage and selection operator (LASSO) (BL) appears to be an interesting approach for fitting marker effects in a regression model. This article adapts the BL to arrive at a regression model where markers, pedigrees, and covariates other than markers are considered jointly. Connections between BL and other marker-based regression models are discussed, and the sensitivity of BL with respect to the choice of prior distributions assigned …
Total citations
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