Authors
Alan TK Wan, Wei Zhao, Peter Gilbert, Yong Zhou
Publication date
2023/6/5
Journal
The international journal of biostatistics
Volume
19
Issue
1
Pages
131-162
Publisher
De Gruyter
Description
Prevalent cohort studies in medical research often give rise to length-biased survival data that require special treatments. The recently proposed varying-coefficient partially linear transformation (VCPLT) model has the virtue of providing a more dynamic content of the effects of the covariates on survival times than the well-known partially linear transformation (PLT) model by allowing flexible interactions between the covariates. However, no existing analysis of the VCPLT model has considered length-biased sampling. In this paper, we consider the VCPLT model when the data are length-biased and right censored, thereby extending the reach of this flexible and powerful tool. We develop a martingale estimating function-based approach to the estimation of this model, provide theoretical underpinnings, evaluate finite sample performance via simulations, and showcase its practical appeal via an empirical application …
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