Authors
Carlos Ferrando, César Aldecoa, Carmen Unzueta, F Javier Belda, Julián Librero, Gerardo Tusman, Fernando Suárez-Sipmann, Salvador Peiró, Natividad Pozo, Andrea Brunelli, Ignacio Garutti, Clara Gallego, Aurelio Rodríguez, Jose Ignacio García, Oscar Díaz-Cambronero, Jaume Balust, Francisco J Redondo, Manuel de la Matta, Lucía Gallego-Ligorit, Javier Hernández, Pascual Martínez, Ana Pérez, Sonsoles Leal, Enrique Alday, Pablo Monedero, Rafael González, Guido Mazzirani, Gerardo Aguilar, Manuel López-Baamonde, Mar Felipe, Ana Mugarra, Jara Torrente, Lucia Valencia, Viviana Varón, Sergio Sánchez, Benigno Rodríguez, Ana Martín, Inmaculada India, Gonzalo Azparren, Rodrigo Molina, Jesús Villar, Marina Soro, Jesús Acosta, María J Alberola, Amalia Alcón, Rosa Almajano, Carlos Álvarez, Rafael Anaya, Cristian Aragón, Marta Argilaga, Blanca Arocas, Begoña Ayas, Victor Balandrón, Elizabeth Bárcena, Natalia Bejarano, Luis Belmonte, Vanesa Berges, Maria Guillén Bermejo, Rafael Cabadas, Sergio Cabrera, Raquel Callejas, Jose Carbonell, Juan Carrizo, Jesús Castillo, Pedro Charco, Ana Colás, Lorena Colomina, Laura Cotter, Patricia Cruz, Javier Cuervo, Gema Del Castillo, Elena Del Río, Juan Delgado, Carlos Dexeus, Rubén Díaz, Mandalina Dinu, Alejandro Duca, Paula Duque, Gemma Echarri, Patricia Fabra, Carmen Fernández, Raluca Florea, Pilar Forcada, Isabel Fuentes, Cristina Garcés, Santiago G Del Valle, Beatriz García, Esther García, María García, Mercedes García, Beatriz Garrigues, Fernando Gil, Domingo González, Alejandro Gracia, Estefanía Gracia, Manuel Granell, Yessica Guerra, Andrea Gutierrez, Julia Hernando, Miriam Herrero, Maite Ibáñez, Inés Imaz, Blanca Izquierdo, Ana Jurado, Noelia Lafuente, Laura Lascorz, Irene León, Antonio López, Daniel López-Herrera, Angels Lozano, José M Marcos, Graciela Martínez, Sara Martínez, Esperanza Mata, Salomé Matoses, Rosa Mendez, María Merino, Andrés Millaruelo, Carlos R Molina, Berta Monleon, Omar M Montenegro, Jose L Muñoz, Pablo Oliver-Forniés, Manuel Ortega, María A Palencia, Ana Parera, Ernesto Pastor, Maria del Mar Pérez, Sara Pérez, David Pestaña, Santiago Piñol, Jaume Puig, Roger Pujol, Natividad Quesada, Ana Ramón, Consuelo Rego, Laura Reviriego, Rayco Rodríguez, Blanca Romero, Esther Romero, Marta Roselló, Lucas Rovira, Lola Ruiz, Laura Sancho, Francisco Sandín, Ferran Serralta, Eva Tres, Paola Valls, Laura Vaquero, Marina Varela
Publication date
2020/1/1
Journal
British journal of anaesthesia
Volume
124
Issue
1
Pages
110-120
Publisher
Elsevier
Description
Background
We aimed to examine whether using a high fraction of inspired oxygen (FIO2) in the context of an individualised intra- and postoperative open-lung ventilation approach could decrease surgical site infection (SSI) in patients scheduled for abdominal surgery.
Methods
We performed a multicentre, randomised controlled clinical trial in a network of 21 university hospitals from June 6, 2017 to July 19, 2018. Patients undergoing abdominal surgery were randomly assigned to receive a high (0.80) or conventional (0.3) FIO2 during the intraoperative period and during the first 3 postoperative hours. All patients were mechanically ventilated with an open-lung strategy, which included recruitment manoeuvres and individualised positive end-expiratory pressure for the best respiratory-system compliance, and individualised continuous postoperative airway pressure for adequate peripheral oxyhaemoglobin …
Scholar articles
C Ferrando, C Aldecoa, C Unzueta, FJ Belda, J Librero… - British journal of anaesthesia, 2020