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This paper explores the use of Flexible Alternating Current Transmission System (FACTS) devices to improve the power system security and availability through an optimal location and parameter settings of FACTS devices. The Nigerian transmission grid was modeled and simulated in PSAT environment as a 5-bus system. Thyristor Control Series Compensator (TCSC) is among the FACTS devices that is capable of reducing transmission line losses and increase the voltage profile of the buses. Here, Genetic Algorithm (GA) optimization technique has been deployed as an effective method of placing TCSC on the Nigerian 330kV Grid System, to control power flow and improve bus voltages. Results obtained show reduction of overall active power losses from the initial 2.1% to 1.5%.