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Segmentation is a crucial phase in image processing because it simplifies the representation of an image and facilitates its analysis. The multilevel thresholding method is more efficient for segmenting digital mammograms compared to the classic bi-level thresholding since it uses a higher number of intensities to represent different regions in the image. In the literature, there are different techniques for multilevel segmentation; however, most of these approaches do not obtain good segmented images. In addition, they are computationally expensive. Recently, statistical criteria such as Otsu, Kapur, and cross-entropy have been utilized in combination with evolutionary and swarm-based strategies to investigate the optimal threshold values for multilevel segmentation. In this paper, an efficient methodology for multilevel segmentation is proposed using the Harris Hawks Optimization (HHO) algorithm and the minimum …