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Infrared spectroscopic analyses of melt inclusions in quartz phenocrysts from pantellerites erupted at Pantelleria, Italy, show that the magmas contained moderate pre-eruptive H₂O contents, ranging from 1.4 to 2.1 wt.%. Melt H₂O concentrations increase linearly with incompatible elements, demonstrating that H₂O contents were not buffered significantly during fractionation by any crystalline or vapor phase. The relatively low H₂O contents of pantellerites are consistent with an origin by partial melting of alkali gabbros rather than fractional crystallization of basalt. Preeruptive H₂O concentrations do not correlate with the volume or explosivity of pantellerite eruptions; decompression history is critical in determining the style of pantellerite (and other) eruptions.