Authors
Beth A Oldmixon, James C Wood, Thomas A Ericsson, Carolyn A Wilson, Mary E White-Scharf, Goran Andersson, Julia L Greenstein, Henk-Jan Schuurman, Clive Patience
Publication date
2002/3
Journal
Journal of virology
Volume
76
Issue
6
Pages
3045
Publisher
American Society for Microbiology (ASM)
Description
Here we report the identification of inbred miniature swine that failed to produce human-tropic replication-competent porcine endogenous retroviruses (HTRC PERVs), using in vitro coculture assays. When HTRC PERVs were isolated from transmitting animals, all were recombinant viruses, with the receptor-binding domain of PERV-A combining with PERV-C-related sequences.
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