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The objective of this study was to determine how a high‐intensity circuit‐training (HICT) program affects key physiological health markers in sedentary obese men. Eight obese (body fat percentage >26%) males completed a four‐week HICT program, consisting of three 30‐minute exercise sessions per week, for a total of 6 hours of exercise. Participants’ heart rate (HR), blood pressure (BP), rating of perceived exertion, total work (TW), and time to completion were measured each exercise session, body composition was measured before and after HICT, and fasting blood samples were measured before throughout, and after HICT program. Blood sample measurements included total cholesterol, triacylglycerides, high‐density lipoprotein cholesterol, low‐density lipoprotein cholesterol, glucose, and insulin. Data were analyzed by paired t‐tests and one‐way ANOVA with repeated measures. Statistical significance …